Random Number Generation, or RNG, is a highly debated topic in almost every competitive video game genre.

Understanding exactly where randomness factors into the equation allows top players to mitigate its negative effects.
Initial Deck Shuffling
If your opponent rushes the bridge and all your cheap defensive counters are at the bottom of your deck, you lose the tower.

Once the initial hand is played, the rotation becomes fixed, and pure skill and memory take over.
Flexibility is a skill.Know what they are holding.It prevents matches from feeling perfectly scripted. Troop Movement Quirks
Another subtle layer of RNG comes from the slight inconsistencies in how the game's AI handles pathfinding.

To counter this, veterans always place defensive buildings in exactly the same specific tiles to guarantee consistent pulls.
Game StyleRNG DependencyAuto-BattlersLuck is the primary factor in individual matchesStandard Tower RushVery Low - Only the starting hand is randomized The Mental Game
Getting angry at a bad starting hand only causes you to make further mistakes and lose the match entirely.

Focus on improving your timing and placement, and let the RNG sort itself out in the long run.